Nexodyn AOS AcidOxidizing Solution by APR.ch is the first active Wound Management cleanser

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STOP STALLING
RESTART HEALING

Nexodyn® AcidOxidizing Solution (AOS) is the Tehclo™ based wound care solution proven to restart healing in stalled wounds.^2,6 A wealth of evidence and real-world experience consistently show accelerated closure¹ with reduced infection rates¹ and less wound-associated pain². So make Nexodyn® AOS a fundamental part of your wound bed preparation routine.

THE RIGHT ANSWER TO CHRONIC WOUND CHALLENGE

A wealth of evidence and real-world experience consistently show that Nexodyn® AOS reduces healing time, protects from risk of infection, reduces clinical signs of local infection and wound associated pain with a highly tolerable profile.^1,2,6

Adding Nexodyn® AOS to the standard of care for diabetic foot ulcers results in faster healing time and protection from risk of infection¹

Significantly faster healing time⁽¹⁾

Significant protection from risk of infection⁽¹⁾

Nexodyn® AOS reduces clinical signs of local infection and wound-associated pain in leg ulcers²

Significantly reduced clinical signs of local infection⁽²⁾

Significantly reduced wound-associated pain⁽²⁾

Nexodyn® AOS is well tolerated. No adverse events associated with the use of Nexodyn® AOS were reported in any of the listed studies.^1,2,6

TEHCLO™: THE NANOTECHNOLOGY BEHIND NEXODYN® AOS^3,4

Tehclo™ is the APR proprietary global patented nanotechnology platform that applies nanoscience to the production of a unique hypochlorous acid (HClO) solution.
Hypochlorous acid is well-known as a broad-spectrum, fast acting antimicrobial agent naturally produced by neutrophils as part of the innate immune system's response to infections.

Unique combination of 3 physicochemical properties

NEXODYN® AOS IN PRACTICE

Nexodyn® AOS is a sprayable solution for Wound Care with ancillary antimicrobial properties intended for use in the debridement, irrigation, cleansing and moistening of chronic wounds and acute wounds, post-surgical wounds, cuts, abrasions, burns and other lesions.⁵

Nexodyn® AOS is a high-tech innovative product - effective, safe and easy to use in wound care ^1,2,6

The product is certified in EU as Class III Medical Device.

References:

Iacopi E. et al. The Use of a Novel Super-Oxidized Solution on Top of Standard Treatment in the Home Care Management of Postsurgical Lesions of the Diabetic Foot Reduces Reinfections and Shortens Healing Time. Int J Low Extrem Wounds. 2018 Dec; 17(4):268-274
Strohal R, et al. The management of critically colonized and locally infected leg ulcers with an Acid-Oxidizing Solution: A pilot study. Adv Skin Wound Care 31(4):163-171, 2018.
Rani SA, Hoon R, Najafi RR, Khosrovi B, Wang L, Debabov D. The in vitro antimicrobial activity of wound and skin cleansers at nontoxic concentrations. Advances in skin & wound care. 2014;27:65-69.
Woods CG, Fu J, Xue P, et al. Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages. Toxicology and applied pharmacology. 2009;238:27-36.
Nexodyn® AcidOxidizing Solution (AOS) [package insert]. Balerna, Switzerland: APR, Applied Pharma Research SA; 2015.
Ricci E, et al. The management of chronic ulcers with an AcidOxidizing Solution. J Wound Care 25(8):443-50, 2016.